Test ID: RNP

Test Name: U1-RNP/ Smith (SM) IgG Antibodies

Test Codes

  • EPIC Code: LAB4803
  • Exsera Order Code: RNP
  • CPT Code: 86235

Specimen Requirements

Specimen Type: Serum

Collection Tube: Serum separator tube (SST) or red top

Collection Instructions: Separate serum from cells ASAP or within 2 hours of collection. Then transfer available serum to a standard transport tube.

Volume Required: 1 mL with a minimum of 500 mcL  

Storage/Transport Temperature: Refrigerated/Frozen

Stability: Ambient (48 Hours) vs Refrigerated (2 weeks) vs frozen (30 days) and avoid freeze/thaw cycles with no more than 2 in total

Unacceptable Conditions: Contaminated, heat-inactivated, containing clots fibrin or gross red blood cells, or severely lipemic hemolyzed or icteric samples

Ordering Recommendation

Reference Interval

Normal Human: <20

Test Classification

This test has been cleared by the US Food and Drug Administration and is used per manufacturer's instructions and per Exsera's SOPs. Performance characteristics were verified by Exsera in a manner consistent with CAP/CLIA requirements.

Methodology

ELISA or EIA

Patient Reporting

5-7 Days

Days Performed: M-F

Aliases

RNP, U1-RNP/ Smith (Sm) IgG Antibodies 

Additional Notes

This test does not differentiate autoantibodies to RNP from Smith due to assay involving immunologically identical binding sites to free Smith antigen in addition to unique binding sites to RNP. To differentiate, Anti-SM autoantibody testing separately is recommended