Test ID: ANAW
Test Name: ANA Profile Without Titer (dsDNA, SM, RNP, SSA, & SSB)
Ordering Recommendation
Recommended for the differential diagnosis of systemic lupus erythematosus (SLE), Sjögren syndrome, and other systemic autoimmune connective tissue diseases. May also be indicative in patients who are ANA-negative but present with clinical features suggestive of Sjögren syndrome or idiopathic inflammatory myopathies, where specific ENA autoantibodies may be present despite a negative ANA screen.
Note: This testing panel includes ENA (Extractable Nuclear Antigen) antibodies and dsDNA antibodies only. It does NOT include ANA by indirect immunofluorescence (IFA).
Test Codes
Specimen Requirements
Specimen Type: Serum
Collection Tube: Serum separator tube (SST) or red top
Collection Instructions: Separate serum from cells ASAP or within 2 hours of collection. Then transfer available serum to a standard transport tube.
Volume Required: 1 mL with a minimum of 500 mcL
Storage/Transport Temperature: Refrigerated/Frozen
Stability: Ambient (up to 8 Hours), refrigerated (up to 2 weeks/14days), frozen (up to 30 days) and avoid freeze/thaw cycles with no more than 3 in total
Unacceptable Conditions: Contaminated, heat-inactivated, containing clots fibrin or gross red blood cells, or severely lipemic hemolyzed or icteric samples
Indvidual Test Components
Test Code
LAB5254
LAB4559
LAB4803
LAB344
LAB345
Method
Fluoroenzyme Immunassay
ELISA or EIA
ELISA or EIA
ELISA or EIA
ELISA or EIA
Reference Interval
See Individual tests for more information
Test Classification
This test has been cleared by the US Food and Drug Administration and is used per manufacturer's instructions and per Exsera's SOPs. Performance characteristics were verified by Exsera in a manner consistent with CAP/CLIA requirements.
Methodology
See Individual test above
Patient Reporting
5 Business Days
Days Performed: M-F
Aliases
ANAW. ANA profile without titer